All-time best penalty takers
| # | Name | Matches | 11m | |
|---|---|---|---|---|
| 1 |  | Nicolás Sánchez | 168 | 24 |
| 2 |  | Dorlan Pabón | 274 | 16 |
 | Humberto Suazo | 248 | 16 | |
| 4 |  | Rogelio Funes Mori | 310 | 12 |
 | Sergio Canales | 118 | 12 | |
| 6 |  | Luis Pérez | 359 | 10 |
| 7 |  | Lucas Ocampos | 86 | 8 |
| 8 |  | Sergio Ramos | 34 | 5 |
| 9 |  | Edwin Cardona | 87 | 4 |
 | Vincent Janssen | 93 | 4 | |
| 11 |  | Avilés Hurtado | 127 | 3 |
 | Carlos Sánchez | 98 | 3 | |
| 13 |  | Walter Ayoví | 262 | 2 |
 | Arturo González | 229 | 2 | |
 | Osvaldo Martínez | 112 | 2 | |
 | Maximiliano Meza | 238 | 2 | |
| 17 |  | Rodrigo Aguirre | 63 | 1 |
 | Marcelino Bernal | 5 | 1 | |
 | Germán Berterame | 153 | 1 | |
 | Hugo Cuypers | 20 | 1 | |
 | Aldo de Nigris | 218 | 1 | |
 | Ángel Reyna | 48 | 1 | |
 | Brandon Vázquez | 50 | 1 | |
 | Duván Vergara | 37 | 1 | |
 | Zinha | 11 | 1 |