Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 06/2022 |  | César Munder | FW |  | Universidad Católica | U. Católica |
| 01/2022 |  | Gastón Lezcano | FW | |||
| 01/2022 |  | Cecilio Waterman | FW | |||
| 01/2022 |  | Iván Villalba | DF | |||
| 01/2022 | | Mauro González | MF | |||
| 01/2022 |  | Nelson Sepúlveda | MF | |||
| 01/2022 | | Jorge Deschamps | GK |  | Rangers | Rangers |
| 01/2022 | | Francisco Alarcón | DF |  | Universidad de Concepción | Universidad de Concepción |
| 01/2022 | | Marcelo Jorquera | DF |  | Unión Española | Unión Española |
| 01/2022 | | Guillermo Pacheco | DF |  | Deportes Temuco | Deportes Temuco |
| 01/2022 | | Alejandro Camargo | MF |  | Deportes Melipilla | Dep. Melipilla |
| 01/2022 | | Matías Fredes | MF |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 | | Marcos Pol | FW | | Rangers | Rangers |
| 02/2022 | | Juan Vieyra | MF |  | CD Marathón | CD Marathón |
| 01/2022 | | Felipe Reynero | FW |  | Ñublense | Ñublense |
| 01/2022 | | José Gamonal | GK |  | Fernández Vial | Fernandez Vial |
| 01/2022 | | Rodolfo González | DF |  | Cobreloa | Cobreloa |
| 01/2022 | | Mario Pardo | DF |  | Deportes Iquique | Deportes Iquique |
| 01/2022 | | Francisco Ayala | MF |  | Santiago Morning | Morning |
| 01/2022 | | Eduardo Farías | MF | | Cobreloa | Cobreloa |
| 01/2022 | | Diego González Saavedra | MF |  | O'Higgins | O'Higgins |
| 01/2022 | | Cristian Maidana | MF |  | Boca Unidos | Boca Unidos |
| 01/2022 | | Franco Ragusa | MF | | Universidad de Concepción | Universidad de Concepción |
| 01/2022 | | Iván Smith | MF |  | Godoy Cruz II | Godoy Cruz II |
| 01/2022 | | Matías Donoso | FW | | Deportes Temuco | Deportes Temuco |
| 01/2022 |  | Brayan Hurtado | FW |  | Antofagasta | Antofagasta |
| 01/2022 | | Sebastián Varas | FW |  | Puerto Montt | Puerto Montt |