Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 12/2022 |  | Walter Pandiani | MA | |||
| 09/2022 | | Sebastián Jaume | GK | |||
| 07/2022 | | Gastón Sánchez | MF | |||
| 07/2022 | | Nahuel Acosta | MF | |||
| 07/2022 | | Alejo Cruz | MF |  | Peñarol | Peñarol |
| 07/2022 | | Kevin Lewis | MF | | Peñarol | Peñarol |
| 07/2022 | | Juan Bado | DF | |||
| 07/2022 | | Ezequiel Burdín | DF | |||
| 07/2022 | | Bautista Pérez | DF | |||
| 07/2022 | | Martín Iglesias | MF | |||
| 07/2022 | | Felipe Rodríguez | MF | |||
| 07/2022 | | Juan Vire | MF | |||
| 02/2022 |  | Ousmane N'Dong | DF | |||
| 01/2022 | | Santiago Cappi | DF | |||
| 01/2022 | | Alberto Eiraldi | GK |  | Cerrito | Cerrito |
| 01/2022 | | Yonatan Irrazábal | GK |  | Rentistas | Rentistas |
| 01/2022 | | Emiliano Ancheta | DF |  | Cerro Largo | Cerro Largo |
| 01/2022 | | Mauro García | DF |  | Rocha | Rocha |
| 01/2022 | | Mathías Goyeni | DF | | Cerrito | Cerrito |
| 01/2022 | | Ángelo Pizzorno | DF |  | Aucas | SD Aucas |
| 01/2022 | | Federico Platero | DF |  | Unión Española | Unión Española |
| 01/2022 | | Martín Barríos | MF |  | Racing | Racing |
| 01/2022 | | Cristian Barros | MF |  | Defensor Sporting | Defensor |
| 01/2022 | | José Neris | MF |  | River Plate | River Plate |
| 01/2022 | | Agustín Pons | MF |  | Montevideo City Torque | Torque |
| 01/2022 | | Ányelo Rodríguez | MF | | Racing | Racing |
| 01/2022 | | Jairo Villalpando | MF |  | Central Español | Español |
| 01/2022 | | Gianluca Colla | FW | |||
| 01/2022 | | Federico Rodríguez | FW | | Cerrito | Cerrito |
| 01/2022 | | Ignacio Risso | MA |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 | | Gustavo Vargas | GK |  | Colón | Colón |
| 06/2022 | | Cristian Sención | MF |  | Gualaceo SC | Gualaceo SC |
| 03/2022 | | Stéfano Cetrulo | FW |  | Oriental | Oriental |
| 01/2022 | | Washington Ortega | GK |  | Internacional de Bogotá | La Equidad |
| 01/2022 | | Facundo Cabrera | DF | | Central Español | Español |
| 01/2022 | | Tabaré Da Cunha | DF |  | Rampla Juniors | Rampla Juniors |
| 01/2022 | | Federico Velázquez | DF | | Rampla Juniors | Rampla Juniors |
| 01/2022 | | Pablo González | MF |  | Liverpool | Liverpool FC |
| 01/2022 | | Christian Yeladian | MF |  | Bella Vista | Bella Vista |
| 01/2022 | | Fernando Arismendi | FW |  | Blooming | Blooming |
| 01/2022 | | Nicolás Brun | FW |  | Ramón Santamarina | Santamarina |
| 01/2022 | | Darlyn Gayol | MA | | Rampla Juniors | Rampla Juniors |