Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2021 |  | Gonzalo Papa | MF |  | Ayacucho FC | Ayacucho |
| 06/2021 |  | Marlon González | GK | |||
| 06/2021 | | Delis Vargas | FW |  | Real España | Real España |
| 04/2021 | | Agustín Hernández | DF |  | CA Cerro | CA Cerro |
| 04/2021 |  | Mauro Burruchaga | MF |  | Deportivo Maldonado | Maldonado |
| 04/2021 | | Cristian Sención | MF |  | Rampla Juniors | Rampla Juniors |
| 04/2021 | | Rodrigo Izquierdo | DF | | CA Cerro | CA Cerro |
| 04/2021 | | Leandro Zazpe | DF | |||
| 04/2021 | | Fernando Arismendi | FW | |||
| 03/2021 | | Francisco Ibañez | DF |  | Racing | Racing |
| 03/2021 | | Maximiliano Callorda | FW | | Ayacucho FC | Ayacucho |
| 03/2021 | | Santiago Correa | MF | | Real España | Real España |
| 03/2021 | | Facundo Cabrera | DF | |||
| 01/2021 | | Leonardo Barrios | DF | |||
| 01/2021 | | Theo Casavalle | MF | |||
| 01/2021 | | Juan Muguerza | MF | |||
| 01/2021 | | Stéfano Cetrulo | FW | |||
| 01/2021 |  | Kevin Hurtado | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2021 | | Leonardo Barrios | DF |  | Parque del Plata | Parque |
| 07/2021 | | Maximiliano Ohaco | FW |  | Bella Vista | Bella Vista |
| 05/2021 | | Gonzalo Bazallo | MF | | Rampla Juniors | Rampla Juniors |
| 04/2021 | | Lucas Ruíz | DF |  | Villa Teresa | Villa Teresa |
| 03/2021 | | Franco García | FW |  | Cerro Largo | Cerro Largo |