Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2022 |  | Víctor Antelo | MA | |||
| 08/2022 |  | Néstor Clausen | MA | |||
| 07/2022 | | César Romero | DF | |||
| 07/2022 |  | Júnior Brítez | MF | |||
| 07/2022 | | Ramiro Eguez | FW | |||
| 07/2022 | | Sergio Ferreira | FW |  | Blooming U20 | Club Blooming U20 |
| 06/2022 | | Jorge Lovera | MF |  | Real Tomayapo | Tomayapo |
| 06/2022 | | José Carrasco | DF |  | Universidad de Chile | Uni. de Chile |
| 02/2022 |  | Darlan | DF |  | Aimoré - RS | Aimoré |
| 01/2022 | | Jesús Sagredo | DF | |||
| 01/2022 | | Yassier Sánchez | GK | |||
| 01/2022 | | Marcelo De Lima | DF | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Nahuel Iribarren | DF |  | Platense | Platense |
| 01/2022 | | Mario Perez | DF | |||
| 01/2022 | | Gustavo Visalla | DF | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Cristian Arano | MF |  | Jorge Wilstermann | Wilstermann |
| 01/2022 | | José Balcazar | MF | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Denilson Durán | MF | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Andrés Gandarillas | MF | |||
| 01/2022 | | Erwin Sánchez | MF |  | The Strongest | The Strongest |
| 01/2022 |  | Fernando Arismendi | FW |  | Albion | Albion |
| 01/2022 | | Jefferson da Silva | FW |  | Royal Pari | Royal Pari |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 | | Andrés Veizaga | FW |  | Real Santa Cruz | Santa Cruz |
| 04/2022 | | Robert Cueto | DF |  | Atlético Warnes | Atlético Warnes |
| 03/2022 | | Omar Lijerón | MF |  | Torre Fuerte | Torre Fuerte |
| 01/2022 | | Rafael Barros | FW |  | Botafogo - PB | Botafogo PB |
| 01/2022 | | Fabricio Castillo | GK | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Marco Vaca | GK | | Real Santa Cruz | Santa Cruz |
| 01/2022 | | Oscar Baldomar | DF |  | Nacional Potosí | Nacional Potosí |
| 01/2022 | | Daniel Lino | DF | | Blooming U20 | Club Blooming U20 |
| 01/2022 | | Oscar Ribera | DF | | The Strongest | The Strongest |
| 01/2022 | | Leonardo Urapuca | DF |  | Universitario de Sucre | Universitario |
| 01/2022 | | Alan Farell | MF | | Real Santa Cruz | Santa Cruz |
| 01/2022 | | Helmut Gutiérrez | MF | | Universitario de Sucre | Universitario |
| 01/2022 | | Walter Rioja | FW |  | Atlético Palmaflor | Palmaflor |