Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2022 |  | Matías Cano | GK |  | Coquimbo Unido | Coquimbo Unido |
| 01/2022 |  | Miguel Escalona | DF |  | Deportes Melipilla | Dep. Melipilla |
| 01/2022 | | Rodolfo González | DF |  | Cobresal | CD Cobresal |
| 01/2022 | | Rivaldo Hernández | DF | |||
| 01/2022 | | Bastián San Juan | DF |  | CD Magallanes | CD Magallanes |
| 01/2022 | | Juan Soto | DF |  | Santiago Wanderers | Wanderers |
| 01/2022 | | Matías Ballini | MF |  | San Martín de Tucumán | CASMT |
| 01/2022 | | Eduardo Farías | MF | | Cobresal | CD Cobresal |
| 01/2022 | | Mathías López | MF |  | Deportes Concepción | Concepción |
| 01/2022 | | Tomás Ortiz | MF |  | Defensa y Justicia II | Defensa y Justicia II |
| 01/2022 | | Christian Pavéz | MF |  | San Marcos | San Marcos |
| 01/2022 | | Carlos Sepúlveda | MF |  | Fernández Vial | Fernandez Vial |
| 01/2022 | | Maximiliano Cerato | FW |  | Everton | Everton |
| 01/2022 | | Roberto Gutiérrez | FW |  | Ñublense | Ñublense |
| 01/2022 | | Diego Ignacio Silva Valderrama | AS-CO |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 03/2022 | | Fernando Barrientos | MF |  | All Boys | All Boys |
| 02/2022 | | Ricardo Matamala | MF |  | San Antonio Unido | San Antonio |
| 01/2022 |  | Sebastián Ramírez | DF |  | AD Tarma | Tarma |
| 01/2022 | | Álvaro Césped | MF |  | Unión San Felipe | San Felipe |
| 01/2022 | | Bryan Cortés | MF |  | Recoleta | Recoleta |
| 01/2022 | | Ronald González | MF |  | Deportes Copiapó | Deportes Copiapó |
| 01/2022 | | Bastian Valdés | MF | | San Antonio Unido | San Antonio |
| 01/2022 | | Pablo Brito | FW |  | Santa Cruz | Santa Cruz |
| 01/2022 |  | Gustavo Guerreño | FW |  | Universidad de Concepción | Universidad de Concepción |
| 01/2022 | | Patricio Romero | FW |  | Real San Joaquín | San Joaquín |
| 01/2022 | | Carlos Ross | FW |  | Sport Huancayo | Huancayo |
| 01/2022 | | Gabriel Tellas | FW |  | Academia Cantolao | AD Cantolao |