| Date | Round | Round | H/A | Res. | |||
|---|---|---|---|---|---|---|---|
| 23.01.2010 | Matchday 1 | Matchday 1 | H | ![]() | Liverpool FC | L | 1:41:3 |
| 30.01.2010 | Matchday 2 | Matchday 2 | H | ![]() | Cerro Largo | D | 1:10:1 |
| 06.02.2010 | Matchday 3 | Matchday 3 | H | ![]() | CA Cerro | L | 1:41:2 |
| 13.02.2010 | Matchday 4 | Matchday 4 | A | ![]() | Wanderers | W | 2:12:1 |
| 20.02.2010 | Matchday 5 | Matchday 5 | H | ![]() | Racing | W | 3:02:0 |
| 28.02.2010 | Matchday 6 | Matchday 6 | A | ![]() | Tacuarembó | L | 0:10:1 |
| 07.03.2010 | Matchday 7 | Matchday 7 | H | ![]() | Defensor | W | 2:00:0 |
| 14.03.2010 | Matchday 8 | Matchday 8 | A | ![]() | Danubio | L | 0:10:0 |
| 20.03.2010 | Matchday 9 | Matchday 9 | H | ![]() | Fénix | L | 1:20:1dec. |
| 28.03.2010 | Matchday 10 | Matchday 10 | A | ![]() | River Plate | L | 0:30:0 |
| 04.04.2010 | Matchday 11 | Matchday 11 | A | ![]() | Peñarol | L | 1:31:2 |
| 11.04.2010 | Matchday 12 | Matchday 12 | H | ![]() | Español | L | 1:31:2 |
| 17.04.2010 | Matchday 13 | Matchday 13 | H | ![]() | Rampla Juniors | D | 1:10:0 |
| 25.04.2010 | Matchday 14 | Matchday 14 | H | ![]() | Atenas | W | 2:01:0 |
| 02.05.2010 | Matchday 15 | Matchday 15 | A | ![]() | Nacional | L | 1:30:1 |
Cerrito















