| Date | Round | Round | H/A | Res. | |||
|---|---|---|---|---|---|---|---|
| 26.08.2009 | Matchday 1 | Matchday 1 | A | ![]() | Liverpool FC | L | 3:41:0 |
| 30.08.2009 | Matchday 2 | Matchday 2 | A | ![]() | Cerro Largo | W | 1:00:0 |
| 13.09.2009 | Matchday 3 | Matchday 3 | A | ![]() | CA Cerro | W | 2:00:0 |
| 20.09.2009 | Matchday 4 | Matchday 4 | H | ![]() | Wanderers | L | 1:21:0 |
| 27.09.2009 | Matchday 5 | Matchday 5 | A | ![]() | Racing | D | 1:10:1 |
| 04.10.2009 | Matchday 6 | Matchday 6 | H | ![]() | Tacuarembó | W | 2:00:0 |
| 18.10.2009 | Matchday 7 | Matchday 7 | A | ![]() | Defensor | L | 0:10:0 |
| 22.10.2009 | Matchday 8 | Matchday 8 | H | ![]() | Danubio | D | 2:22:0 |
| 28.10.2009 | Matchday 9 | Matchday 9 | A | ![]() | Fénix | D | 0:00:0 |
| 31.10.2009 | Matchday 10 | Matchday 10 | H | ![]() | River Plate | D | 1:10:1 |
| 08.11.2009 | Matchday 11 | Matchday 11 | H | ![]() | Peñarol | D | 2:20:0 |
| 22.11.2009 | Matchday 12 | Matchday 12 | A | ![]() | Español | D | 2:21:2 |
| 05.12.2009 | Matchday 13 | Matchday 13 | A | ![]() | Rampla Juniors | L | 0:10:0 |
| 09.12.2009 | Matchday 14 | Matchday 14 | A | ![]() | Atenas | W | 1:01:0 |
| 13.12.2009 | Matchday 15 | Matchday 15 | H | ![]() | Nacional | L | 2:51:3 |
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