Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 |  | Marco Medel | MF |  | Santiago Wanderers | Wanderers |
| 07/2021 | | Matías Osorio | DF | |||
| 06/2021 | | David Salazar | FW |  | O'Higgins | O'Higgins |
| 04/2021 | | Marcelo Filla | DF | |||
| 03/2021 |  | Nilo Carretero | AS-CO | |||
| 03/2021 | | Nicolás Núñez | MA | |||
| 03/2021 | | Matías Persia | FW |  | Deportivo Maipú | Maipú |
| 03/2021 | | Bastián San Juan | DF |  | Everton | Everton |
| 03/2021 | | Miguel Orellana | MF |  | Santiago Morning | Morning |
| 02/2021 |  | Gastón Rodríguez | GK |  | Deportes Valdivia | Valdivia |
| 02/2021 | | Mikel Arguinarena | MF |  | Barnechea | Barnechea |
| 02/2021 | | Sebastián Pérez | FW |  | Ñublense | Ñublense |
| 02/2021 |  | Jermein Peña | DF |  | Unión Magdalena | Unión Magdalena |
| 02/2021 | | Miguel Jiménez | GK | | Ñublense | Ñublense |
| 02/2021 | | Claudio Jopia | DF |  | Cobreloa | Cobreloa |
| 01/2021 | | Marko Biskupovic | DF |  | La Serena | La Serena |
| 01/2021 |  | Jonathan Espinola | DF | |||
| 01/2021 | | Matías Vásquez | DF | |||
| 01/2021 | | Javier Quiroz | MF |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 | | Matías Persia | FW |  | All Boys | All Boys |
| 08/2021 | | Jermein Peña | DF | | Unión Magdalena | Unión Magdalena |
| 03/2021 | | Santiago Molina | DF |  | Belgrano de San Francisco | Belgrano |
| 03/2021 | | Camilo Melivilú | FW |  | Puerto Montt | Puerto Montt |
| 03/2021 | | Ricardo Escobar | DF |  | Coquimbo Unido | Coquimbo Unido |
| 02/2021 |  | Ricardo Adé | DF |  | Mushuc Runa | Mushuc Runa |
| 02/2021 | | Emiliano Bahamondes | MF |  | San Antonio Unido | San Antonio |
| 02/2021 | | Carlos Soza | MF |  | Deportes Copiapó | Deportes Copiapó |
| 01/2021 | | Diego Sanchez | MF |  | Provincial Ranco | Provincial |