Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 12/2022 |  | Joey Akpunonu | DF |  | FC Cincinnati 2 | FC Cincinnati 2 |
| 11/2022 |  | Stiven Jimenez | MF |  | Team México U17 | Team México U17 |
| 08/2022 | | Evan Louro | GK | |||
| 08/2022 | | Matt Miazga | DF |  | Chelsea FC | Chelsea |
| 07/2022 |  | Sergio Santos | FW |  | Philadelphia Union | Philadelphia |
| 04/2022 |  | Obinna Nwobodo | MF |  | Göztepe | Göztepe Izmir |
| 02/2022 |  | Júnior Moreno | MF |  | D.C. United | DC United |
| 01/2022 | | Kenny Arena | AS-CO | |||
| 01/2022 | | Dominic Kinnear | AS-CO | |||
| 01/2022 | | Ian Murphy | DF | |||
| 01/2022 | | Nick Markanich | FW | |||
| 01/2022 | | John Nelson | DF |  | FC Dallas | FC Dallas |
| 01/2022 | | Ray Gaddis | DF | |||
| 01/2022 |  | Dom Badji | FW |  | Colorado Rapids | Colorado Rapids |
| 01/2022 | | Roman Celentano | GK |  | Indiana Hoosiers | Indiana Hoosiers |
| 01/2022 | | Ben Mines | MF |  | Orange County SC | Orange County |
| 01/2022 | | Harrison Robledo | MF |  | FC Cincinnati U19 | U19 |
| 01/2022 |  | Jonas Fjeldberg | FW |  | Rio Grande Valley FC | RGV FC |
| 01/2022 |  | Paul Rogers | GK-CO |  | Houston Dynamo | H. Dynamo |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 11/2022 | | John Nelson | DF |  | St. Louis City SC | St. Louis City |
| 08/2022 |  | Haris Medunjanin | MF |  | PEC Zwolle | PEC Zwolle |
| 08/2022 |  | Isaac Atanga | FW | | Göztepe | Göztepe Izmir |
| 03/2022 |  | Gustavo Vallecilla | DF | | Colorado Rapids | Colorado Rapids |
| 03/2022 | | Ben Mines | MF |  | Colorado Springs Switchbacks | Colorado Springs Switchbacks |
| 02/2022 | | Joe Gyau | DF |  | Degerfors IF | Degerfors IF |
| 02/2022 | | Jonas Fjeldberg | FW |  | Indy Eleven | Indy Eleven |
| 01/2022 |  | Ben Lundt | GK |  | Phoenix Rising | Phoenix |
| 01/2022 |  | Maikel van der Werff | DF | | PEC Zwolle | PEC Zwolle |
| 01/2022 |  | Florian Valot | MF |  | Miami FC | Miami FC |
| 01/2022 | | Caleb Stanko | MF |  | PAS Giannina | PAS Giannina |