Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2022 |  | Cristóbal Marín | MF |  | Coquimbo Unido | Coquimbo Unido |
| 07/2022 |  | Jorge Márquez | MF |  | Talleres (RdE) | Talleres |
| 07/2022 | | Emmanuel Ledesma | MF | |||
| 07/2022 | | Rodrigo Osorio | FW | |||
| 04/2022 | | Kennet Lara | DF |  | Curicó Unido | Curicó Unido |
| 02/2022 | | Agustín Volker | DF | | Coquimbo Unido | Coquimbo Unido |
| 01/2022 | | Sebastián Martínez | MF | |||
| 01/2022 | | Mikel Arguinarena | MF | |||
| 01/2022 | | Cristian Campestrini | GK |  | Cancún FC | Cancún |
| 01/2022 | | Javier Cordero | GK |  | Deportes Colina | Colina |
| 01/2022 | | Sebastián Salas | GK | |||
| 01/2022 | | Miguel Arias | DF |  | Fernández Vial | Fernandez Vial |
| 01/2022 | | Vicente López | DF | |||
| 01/2022 | | Luciano Meza | DF | |||
| 01/2022 |  | Camilo Saldaña | DF |  | Rangers | Rangers |
| 01/2022 | | Juan Soriano | DF | |||
| 01/2022 | | Rodrigo Vidal | DF | |||
| 01/2022 | | Juan Araya | MF |  | Limache | Limache |
| 01/2022 | | Gerardo Cortés | MF | |||
| 01/2022 | | Ignacio González | MF | | Rangers | Rangers |
| 01/2022 | | Eduardo Vidal | MF | |||
| 01/2022 | | José Aguilera | FW | | Coquimbo Unido | Coquimbo Unido |
| 01/2022 | | Wladimir Cid | FW |  | General Velásquez | CDGV |
| 01/2022 | | Matías Colossi | FW |  | Deportes Melipilla | Dep. Melipilla |
| 01/2022 | | Juan Duma | FW | | Deportes Melipilla | Dep. Melipilla |
| 01/2022 | | Ignacio Herrera | FW |  | Aucas | SD Aucas |
| 01/2022 |  | Martín Sánchez | FW | |||
| 01/2022 | | Fernando Soto | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 |  | Rodrigo de Olivera | FW |  | Central Español | Español |
| 03/2022 | | Matías Blázquez | DF |  | Santiago Morning | Morning |
| 01/2022 |  | Roger Cañas | MF |  | Shakter Karaganda | Shakter |
| 01/2022 | | Ignacio Ayala | DF |  | Rodelindo Román | Rodelindo |
| 01/2022 | | Pedro Navarro | DF |  | Colo-Colo | Colo-Colo |
| 01/2022 |  | Pablo Pedraza | DF |  | Atlético Palmaflor | Palmaflor |
| 01/2022 | | Benjamin Rojas | DF |  | Palestino | Palestino |
| 01/2022 | | Franz Schultz | MF |  | Santiago Wanderers | Wanderers |
| 01/2022 | | Gaspar Di Pizio | FW |  | Juan Aurich | Juan Aurich |