Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2010 |  | Luis Lugo | GK | |||
| 07/2010 | | José Muñoz | GK | |||
| 07/2010 | | Divar Loras | DF | |||
| 01/2010 |  | Pablo Lanz | GK |  | Sportivo Italiano | Italiano |
| 01/2010 | | Francisco Díaz | DF | |||
| 01/2010 | | Juan Fernández | DF |  | La Paz FC | La Paz FC |
| 01/2010 | | Doyle Vaca | DF |  | The Strongest | The Strongest |
| 01/2010 | | Julio César Cortez | MF | | La Paz FC | La Paz FC |
| 01/2010 | | Carlos Duran | MF | | La Paz FC | La Paz FC |
| 01/2010 | | Daniel Maturana | MF | | La Paz FC | La Paz FC |
| 01/2010 | | Carlos Sabja | MF |  | Blooming | Blooming |
| 01/2010 | | José Suárez | MF | |||
| 01/2010 | | Oliver Fernández | FW |  | Club Aurora | Club Aurora |
| 01/2010 | | Juan Maraude | FW |  | Alianza Atlético | Alianza Atlétic |
| 01/2010 | | Martín Palavicini | FW |  | Club San José | San José |
| 01/2010 | | Iván Zerda | FW |  | Ciclón | Club Ciclón |
| 01/2010 | | Jesús Reynaldo | MA |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2010 | | Pedro Higa | GK | | Club San José | San José |
| 01/2010 | | Juan Robles | GK |  | Universitario de Sucre | Universitario |
| 01/2010 | | Ronald Arana | DF |  | CD Guabirá | CD Guabirá |
| 01/2010 | | Jorge Bruno | DF | | Club San José | San José |
| 01/2010 | | José Suárez | DF | | Club San José | San José |
| 01/2010 |  | Fio | MF | | Club San José | San José |
| 01/2010 | | Alan Loras | MF | | Club San José | San José |
| 01/2010 | | Richard Uriona | MF | | CD Guabirá | CD Guabirá |
| 01/2010 | | Oscar Araúz | FW | | The Strongest | The Strongest |
| 01/2010 | | Jehanamed Castedo | FW |  | Jorge Wilstermann | Wilstermann |
| 01/2010 | | Óscar Díaz | FW | | Club San José | San José |
| 01/2010 | | Marcos Ferrufino | MA | | Club San José | San José |