Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 11/2022 |  | Nicolás Barán | PH-C | |||
| 11/2022 |  | Daniel Farías | MA | |||
| 07/2022 | | Gastón Álvarez | DF | |||
| 07/2022 | | Brian Cordara | FW |  | Cerro Largo | Cerro Largo |
| 07/2022 | | Emiliano Gómez | FW |  | Albacete | Albacete |
| 07/2022 | | Cristian Olivera | FW |  | Peñarol | Peñarol |
| 03/2022 | | Mateo Torres | MF | |||
| 02/2022 | | Maxi Villa | DF |  | Girona FC B | Girona FC B |
| 01/2022 | | Bruno Antúnez | GK | |||
| 01/2022 | | Mauro Goicoechea | GK | |||
| 01/2022 | | Felipe Carvalho | DF |  | River Plate | River Plate |
| 01/2022 | | Santiago Corbo | DF | |||
| 01/2022 | | Leonard Costa | DF |  | Atenas | Atenas |
| 01/2022 | | Joaquín Pereyra | DF |  | Montevideo City Torque | Torque |
| 01/2022 | | Martín Fernández | MF |  | Liverpool | Liverpool FC |
| 01/2022 |  | Jorge Pedra | MF |  | Sud América | Sud América |
| 01/2022 | | Luciano Olaizola | MF |  | Progreso | Progreso |
| 01/2022 | | Rodrigo Pérez | MF | | Atenas | Atenas |
| 01/2022 | | Facundo Rodríguez | MF | | Cerro Largo | Cerro Largo |
| 01/2022 | | Rodrigo Viega | MF | | Liverpool | Liverpool FC |
| 01/2022 | | Martín Boselli | FW |  | Fénix | Fénix |
| 01/2022 | | Brian Leis | FW |  | Uruguay Montevideo | Uru Montevideo |
| 01/2022 |  | Álvaro López | FW |  | Almirante Brown | Almirante Brown |
| 01/2022 | | Agustin Rodríguez | FW |  | Club Nacional | Nacional |
| 01/2022 | | Emiliano Rodríguez | FW | |||
| 01/2022 | | Sebastián Sosa Sánchez | FW |  | Patronato de Paraná | Patronato |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 | | Bruno Barja | FW | | Atenas | Atenas |
| 03/2022 | | Luciano Olaizola | MF | | Progreso | Progreso |
| 02/2022 | | Leandro Lozano | DF |  | Nacional U20 | Nacional U20 |
| 01/2022 | | Gastón Álvarez | DF |  | Getafe CF | Getafe |
| 01/2022 | | Sebastián Sosa Sánchez | FW |  | Vélez Sarsfield | Vélez Sársfield |
| 01/2022 | | Joaquín Pereyra | DF | | Montevideo City Torque | Torque |
| 01/2022 | | Gonzalo Falcón | GK |  | LDU Quito | LDU Quito |
| 01/2022 | | Ramiro Méndez | GK |  | Defensor Sporting | Defensor |
| 01/2022 | | Ismael Tejería | DF | | Progreso | Progreso |
| 01/2022 | | Nicolás Freitas | MF | | Progreso | Progreso |
| 01/2022 | | Leandro Méndez | MF |  | La Luz | La Luz |
| 01/2022 | | Diego Romero | MF |  | Deportivo Maldonado | Maldonado |
| 01/2022 | | Damián Silva | MF | | Defensor Sporting | Defensor |
| 01/2022 | | Gonzalo Bueno | FW |  | Central Español | Español |
| 01/2022 | | Nicolás González | FW | | River Plate | River Plate |
| 01/2022 | | Facundo Labandeira | FW | | Defensor Sporting | Defensor |
| 01/2022 | | Maximiliano Pérez | FW |  | Miramar Misiones | Misiones |
| 01/2022 | | Facundo Rodríguez | FW |  | Mineros de Zacatecas | Zacatecas |