Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 |  | Víctor Antelo | MA | |||
| 07/2021 | | Jhon Velasco | DF | |||
| 07/2021 | | Rudy Colodro | MF | |||
| 07/2021 | | Yohan Pardo | MF | |||
| 07/2021 | | Angel Vaca | MF | |||
| 07/2021 |  | John Mosquera | FW |  | Always Ready | Always Ready |
| 01/2021 | | Juan Zampiery | DF |  | Real Santa Cruz | Santa Cruz |
| 01/2021 |  | Federico Domínguez | MF |  | Real Potosí | Real Potosí |
| 01/2021 | | Carlos Abastoflor | FW | |||
| 01/2021 | | William Álvarez | FW |  | Jorge Wilstermann | Wilstermann |
| 01/2021 | | Alan Mercado | FW |  | Oriente Petrolero | Petrolero |
| 01/2021 |  | Kevin Mina | FW |  | Olmedo | Olmedo |
| 01/2021 | | Brayan Sosa | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2021 | | Marco Andia | MF |  | Nacional Potosí | Nacional Potosí |
| 02/2021 | | Alejandro Bejarano | DF |  | Independiente Petrolero | Independiente |
| 01/2021 | | Jesús Flores | DF | | Real Santa Cruz | Santa Cruz |
| 01/2021 | | Ricardo Suárez | DF | | Real Santa Cruz | Santa Cruz |
| 01/2021 | | Erick Iragua | MF |  | Universitario de Vinto | Universitario de Vinto |
| 01/2021 | | Jorge Lovera | MF | | Real Potosí | Real Potosí |