Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 |  | Hugo Silveira | FW | |||
| 08/2021 |  | Sebastián Contreras | DF |  | Juventud de Las Piedras | Juventud |
| 08/2021 | | Joe Abrigo | MF |  | Unión Española | Unión Española |
| 07/2021 | | Maximiliano Torrealba | MF | |||
| 06/2021 | | Sebastián Pino | MF |  | CSD Lautaro | Lautaro |
| 03/2021 | | Nicolás Guerra | FW |  | Universidad de Chile | Uni. de Chile |
| 03/2021 |  | Matías Moya | FW |  | River Plate II | River Plate II |
| 03/2021 | | Enzo Guerrero | DF |  | Palestino | Palestino |
| 03/2021 | | Alison Pérez | GK |  | Progreso | Progreso |
| 03/2021 | | Esteban Carvajal | MF | | Palestino | Palestino |
| 03/2021 | | Roberto Gutiérrez | FW |  | O'Higgins | O'Higgins |
| 03/2021 | | Maximiliano Quinteros | FW | |||
| 02/2021 | | Rafael Caroca | DF |  | Deportes Iquique | Deportes Iquique |
| 02/2021 | | Branco Provoste | MF |  | Colo-Colo | Colo-Colo |
| 02/2021 | | Manuel Rivera | MF |  | Barnechea | Barnechea |
| 02/2021 | | Fernando Cordero | DF |  | Unión La Calera | La Calera |
| 02/2021 | | Bernardo Cerezo | DF |  | Santiago Wanderers | Wanderers |
| 02/2021 | | Hernán Muñoz | GK |  | Deportes Copiapó | Deportes Copiapó |
| 02/2021 | | Fabricio Fontanini | DF |  | Newell's Old Boys | Newell's OB |
| 01/2021 | | Guillermo Guajardo | GK | |||
| 01/2021 |  | Tomás Rojas | MF |  | Sol de América | Sol de América |
| 01/2021 | | Diego Sepúlveda | MF |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2021 | | Fabricio Fontanini | DF |  | Aucas | SD Aucas |
| 06/2021 | | Juan Araya | MF |  | Limache | Limache |
| 04/2021 | | Rodrigo Odriozola | GK |  | Racing | Racing |
| 03/2021 | | Jorge Orellana | MF |  | Puerto Montt | Puerto Montt |
| 03/2021 | | David Escalante | FW |  | Cobreloa | Cobreloa |
| 02/2021 | | Guillermo Avello | DF | | Puerto Montt | Puerto Montt |
| 02/2021 | | Mario Briceño | FW | | CSD Lautaro | Lautaro |
| 02/2021 | | Sebastián Pérez | FW |  | CD Magallanes | CD Magallanes |
| 02/2021 | | Miguel Jiménez | GK | | CD Magallanes | CD Magallanes |
| 02/2021 | | Nicolás Astete | MF |  | Deportes Colina | Colina |
| 02/2021 | | Iván Rozas | MF | | O'Higgins | O'Higgins |
| 02/2021 | | Oscar Ortega | FW |  | Santiago Morning | Morning |