Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 12/2021 |  | Mo Adams | MF |  | Atlanta United FC | Atlanta United |
| 12/2021 |  | Ariel Lassiter | FW |  | Houston Dynamo | H. Dynamo |
| 12/2021 |  | Felipe Valencia | FW |  | Fort Lauderdale CF | Fort Lauderdale |
| 07/2021 | | Ventura Alvarado | DF |  | Atlético San Luis | San Luis |
| 07/2021 | | Indiana Vassilev | FW |  | Aston Villa U21 | Aston Villa U21 |
| 07/2021 |  | Nick Marsman | GK |  | Feyenoord | Feyenoord |
| 07/2021 | | Kieran Gibbs | DF |  | West Bromwich Albion | West Brom |
| 06/2021 | | Drake Callender | GK | | Fort Lauderdale CF | Fort Lauderdale |
| 04/2021 | | Sami Guediri | DF | | Fort Lauderdale CF | Fort Lauderdale |
| 03/2021 |  | Kelvin Leerdam | DF |  | Seattle Sounders | Seattle SFC |
| 03/2021 |  | Joevin Jones | DF | |||
| 03/2021 |  | Gregore | MF |  | Bahia - BA | Bahia |
| 02/2021 | | Ryan Shawcross | DF |  | Stoke City | Stoke City |
| 01/2021 | | Dylan Castanheira | GK | | Fort Lauderdale CF | Fort Lauderdale |
| 01/2021 |  | Ian Fray | MF | |||
| 01/2021 |  | Aimé Mabika | DF |  | Kentucky Wildcats | Kentucky Wildcats |
| 01/2021 | | Phil Neville | MA |  | England | England |
| 01/2021 |  | Edison Azcona | FW | | Fort Lauderdale CF | Fort Lauderdale |
| 01/2021 | | Josh Penn | FW |  | Indy Eleven | Indy Eleven |
| 01/2021 | | Alec Scott | G-AN | |||
| 01/2021 |  | Sam Gregory | CH-AN |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 12/2021 |  | Anthony Pulis | AS-CO |  | Miami FC | Miami FC |
| 09/2021 | | Dylan Castanheira | GK |  | San Diego Loyal | San Diego Loyal |
| 06/2021 | | Felipe Valencia | FW | | Fort Lauderdale CF | Fort Lauderdale |
| 05/2021 | | Drake Callender | GK | | Fort Lauderdale CF | Fort Lauderdale |
| 04/2021 | | Patrick Seagrist | DF | | Indy Eleven | Indy Eleven |
| 04/2021 | | Dylan Nealis | MF |  | Nashville SC | Nashville SC |
| 03/2021 | | Juan Agudelo | FW |  | Minnesota United FC | Minnesota Utd |
| 01/2021 | | Alvas Powell | DF |  | Al Hilal Omdurman | Al Hilal EC |
| 01/2021 | | Jerome Kiesewetter | FW |  | FC Tulsa | FC Tulsa |
| 01/2021 |  | A.J. DeLaGarza | DF |  | New England Revolution | New Engl. |
| 01/2021 | | Wil Trapp | MF | | Minnesota United FC | Minnesota Utd |
| 01/2021 |  | Andrés Reyes | DF |  | Atlético Nacional | Atl. Nacional |