Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 |  | Alejandro Sánchez | GK |  | Central Córdoba SdE | Central Córdoba |
| 08/2021 |  | Carlos Muñoz | FW |  | Antofagasta | Antofagasta |
| 08/2021 | | Miguel Ramírez | MA | |||
| 08/2021 | | Cristián Reynero | AS-CO | |||
| 07/2021 | | Pablo Hernández | MF |  | Independiente | Independiente |
| 06/2021 | | Matías Belmar | FW |  | O'Higgins U20 | U20 |
| 04/2021 | | Diego Carreño | GK | | O'Higgins U20 | U20 |
| 03/2021 | | Nelson Espinoza | GK |  | Universidad de Chile | Uni. de Chile |
| 03/2021 | | Ronald Guzmán | DF | |||
| 03/2021 | | Raúl Osorio | DF |  | Coquimbo Unido | Coquimbo Unido |
| 03/2021 | | Cristóbal Castillo | MF | |||
| 03/2021 | | Felipe Seymour | MF |  | Unión La Calera | La Calera |
| 03/2021 | | Fabián Hormazábal | FW |  | La Serena | La Serena |
| 02/2021 | | Iván Rozas | MF |  | Ñublense | Ñublense |
| 02/2021 | | David Salazar | FW |  | Santa Cruz | Santa Cruz |
| 01/2021 | | Alberto Letelier | MF |  | O'Higgins U17 | U17 |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 | | Gustavo Gotti | FW |  | Fernández Vial | Fernandez Vial |
| 07/2021 | | Augusto Batalla | GK |  | San Lorenzo | CASL |
| 07/2021 | | Tomás Alarcón | MF |  | Cádiz CF | Cádiz |
| 06/2021 | | David Salazar | FW |  | CD Magallanes | CD Magallanes |
| 05/2021 | | Hugo Herrera | MF |  | Colchagua | Colchagua |
| 04/2021 | | Gerardo Navarrete | MF |  | Unión Española | Unión Española |
| 04/2021 | | Gastón Zúñiga | DF | | Santa Cruz | Santa Cruz |
| 04/2021 | | Diego González Saavedra | MF |  | Cobresal | CD Cobresal |
| 03/2021 | | Luis Ureta | GK |  | San Marcos | San Marcos |
| 03/2021 | | Paulo Magalhaes | DF | | Antofagasta | Antofagasta |
| 03/2021 | | Roberto Gutiérrez | FW | | Ñublense | Ñublense |
| 03/2021 | | José Luis Muñoz | FW |  | Deportes Melipilla | Dep. Melipilla |
| 02/2021 | | Roberto Cereceda | DF |  | Audax Italiano | Audax Italiano |