Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 09.01.2022 |  | Matchday 17 | Águilas FC - CS Puertollano | - CSP | 1:0 | |
| 30.01.2022 | | Matchday 19 | Águilas FC - CD Toledo | - Tol | 1:3 | |
| 13.02.2022 | | Matchday 21 | Águilas FC - Recre Granada | - | 0:0 | |
| 27.02.2022 | | Matchday 23 | Águilas FC - Mar Menor CF | - | 2:0 | |
| 13.03.2022 | | Matchday 25 | Águilas FC - UD Socuéllamos | - SOC | 2:2 | |
| 27.03.2022 | | Matchday 27 | Águilas FC - Levante B | - Lev | 2:1 | |
| 10.04.2022 | | Matchday 29 | Águilas FC - CF La Nucía | - | 2:0 | |
| 24.04.2022 | | Matchday 31 | Águilas FC - Hércules | - HER | 1:1 | |
| 08.05.2022 | | Matchday 33 | Águilas FC - UD Melilla | - MEL | 0:1 |