Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 27.01.2021 |  | Matchday 4 | Chania - Ergotelis | CFC - Erg | 0:1 | |
| 03.02.2021 | | Matchday 1 | Chania - Doxa Dramas FC | CFC - | 1:0 | |
| 07.02.2021 | | Matchday 6 | Chania - Trikala | CFC - | 1:2 | |
| 13.02.2021 | | Matchday 8 | Chania - OFI Ierapetra | CFC - | 1:0 | |
| 17.02.2021 | | Matchday 9 | Chania - Panachaiki GE | CFC - Pan | 0:0 | |
| 27.02.2021 | | Matchday 11 | Chania - Ionikos | CFC - Ion | 0:1 | |
| 07.03.2021 | | Matchday 13 | Chania - Levadiakos | CFC - Lev | 0:0 | |
| 13.03.2021 | | Matchday 14 | Chania - Karaiskakis | CFC - | 1:0 | |
| 21.03.2021 | | Matchday 16 | Chania - Xhanti FC | CFC - Xan | 0:0 | |
| 03.04.2021 | | Matchday 18 | Chania - Diagoras FC | CFC - DFC | 1:0 | |
| 18.04.2021 | | Matchday 21 | Chania - Apollon Lárissa | CFC - | 2:1 | |
| 05.05.2021 | | Matchday 2 | Chania - Ionikos | CFC - Ion | 1:0 | |
| 19.05.2021 | | Matchday 5 | Chania - Diagoras FC | CFC - DFC | 2:0 | |
| 25.09.2021 |  | 3. Round | Aris Soudas - Diagoras FC | - DFC | 0:1 | |
| 24.11.2021 | | Matchday 4 | Chania - AS Rhodos | CFC - | 2:2 | |
| 05.12.2021 | | Matchday 6 | Chania - AE Kifisias | CFC - | 3:0 | |
| 15.12.2021 | | Matchday 8 | Chania - Kalamata | CFC - | 1:2 | |
| 29.12.2021 | | Matchday 10 | Chania - Karaiskakis | CFC - | 4:0 |