Career as a player
| Period | Team | Country | Position | # | |
|---|---|---|---|---|---|
| 01/2026 - 12/2026 |  | Juventud de Las Piedras |  Uruguay | Defence | 4 |
| 02/2025 - 06/2025 |  | Libertad |  Paraguay | Defence | 3 |
| 08/2022 - 02/2025 |  | Los Angeles Galaxy |  USA | Defence | 22 |
| 01/2023 - 02/2023 |  | Los Angeles Galaxy (Preseason) | USA | Defence | 22 |
| 01/2022 - 06/2022 |  | Levante UD |  Spain | Defence | 7 |
| 09/2021 - 01/2022 |  | Cagliari Calcio |  Italy | Defence | 4 |
| 08/2019 - 06/2021 |  | ACF Fiorentina | Italy | Defence | 22 |
| 07/2019 - 08/2019 |  | Lazio Roma | Italy | Defence | |
| 01/2019 - 06/2019 |  | Juventus | Italy | Defence | 4 |
| 01/2018 - 01/2019 | | Lazio Roma | Italy | Defence | 22 |
| 07/2017 - 01/2018 |  | Hellas Verona | Italy | Defence | 26 |
| 02/2017 - 07/2017 |  | Southampton FC |  England | Defence | 12 |
| 03/2017 - 04/2017 |  | Southampton FC U21 | England | Defence | |
| 01/2012 - 06/2016 | | Juventus | Italy | Defence | 4 |
| 07/2010 - 01/2012 |  | Sevilla FC | Spain | Defence | 4 |
| 08/2009 - 06/2010 | | Juventus | Italy | Defence | 2 |
| 07/2008 - 08/2009 |  | FC Barcelona | Spain | Defence | 2 |
| 07/2007 - 06/2008 |  | Recreativo Huelva | Spain | Defence | 4 |
| 07/2006 - 06/2007 |  | Defensor Sporting | Uruguay | Defence | 22 |
Club matches
| Competition | Matches | Start | In | Out | Min. | Scores | 11m | Ass | Yellow | Yellow-Red | Red | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Champions League | 15 | 12 | 3 | 1 | 1.186 | - | - | 2 | 2 | - | - | » All matches |
| Europa League | 21 | 20 | 1 | 3 | 1.720 | - | - | - | 2 | - | - | » All matches |
| Premier League | 1 | 1 | - | - | 90 | - | - | - | - | - | - | » All matches |
| Serie A | 180 | 148 | 32 | 24 | 13.550 | 12 | - | 3 | 23 | 2 | 1 | » All matches |
| Coppa Italia | 20 | 14 | 6 | 4 | 1.376 | 4 | - | - | 3 | - | - | » All matches |
| Supercoppa | 2 | 1 | 1 | - | 105 | - | - | - | - | - | - | » All matches |
| Primera División | 96 | 87 | 9 | 9 | 7.743 | 4 | - | 4 | 19 | 1 | - | » All matches |
| Copa del Rey | 18 | 16 | 2 | - | 1.536 | 1 | - | - | 7 | - | 1 | » All matches |
 | Copa Libertadores | 14 | 12 | 2 | 1 | 1.181 | - | - | - | 1 | - | - | » All matches |
| Primera División | 2 | 1 | 1 | - | 111 | - | - | - | - | - | - | » All matches |
| Primera División | 12 | 12 | - | 3 | 939 | - | - | - | 3 | 1 | - | » All matches |
 | Leagues Cup | 1 | 1 | - | - | 120 | - | - | - | 1 | - | - | » All matches |
| Major League Soccer | 38 | 36 | 2 | 8 | 2.992 | 2 | - | 1 | 4 | 1 | 1 | » All matches |
| U.S. Open Cup | 3 | 3 | - | - | 270 | - | - | - | - | - | - | » All matches |
| MLS Preseason | 1 | 1 | - | 1 | 30 | - | - | - | - | - | - | » All matches |
| Total | 424 | 365 | 59 | 54 | 32.949 | 23 | - | 10 | 65 | 5 | 3 | ||
| Competition | Matches | Start | In | Out | Min. | Scores | 11m | Ass | Yellow | Yellow-Red | Red | ||
| U21 Premier League 2 | 3 | 3 | - | - | 270 | - | - | - | 1 | - | - | » All matches |
| Total | 3 | 3 | - | - | 270 | - | - | - | 1 | - | - |
International matches
| Competition | Matches | Start | In | Out | Min. | Scores | 11m | Ass | Yellow | Yellow-Red | Red | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | World Cup | 12 | 12 | - | - | 1.080 | - | - | - | 3 | - | - | » All matches |
| WC Qualifiers South America | 39 | 36 | 3 | 4 | 3.179 | 3 | - | 1 | 9 | - | 1 | » All matches |
| WC Qualifiers Play-offs | 2 | 2 | - | - | 180 | - | - | - | - | - | - | » All matches |
| Friendlies | 47 | 41 | 6 | 6 | 3.708 | 1 | - | 1 | 7 | 1 | - | » All matches |
| Confederations Cup | 4 | 4 | - | - | 390 | - | - | - | - | - | - | » All matches |
| Copa América | 12 | 9 | 3 | 1 | 987 | - | - | 1 | 4 | - | - | » All matches |
| Total | 116 | 104 | 12 | 11 | 9.524 | 4 | - | - | 23 | 1 | 1 | ||
| Competition | Matches | Start | In | Out | Min. | Scores | 11m | Ass | Yellow | Yellow-Red | Red | ||
| U20 World Cup | 4 | 4 | - | 1 | 387 | - | - | - | - | - | - | » All matches |
| U20 Campeonato Sudamericano | 7 | 7 | - | - | 630 | - | - | - | 4 | - | - | » All matches |
| Total | 11 | 11 | - | 1 | 1.017 | - | - | - | 4 | - | - |