All-time best penalty takers
| # | Name | Matches | 11m | |
|---|---|---|---|---|
| 1 |  | Nico Olivera | 127 | 13 |
| 2 |  | Álvaro Navarro | 171 | 10 |
| 3 |  | Ignacio Risso | 177 | 8 |
| 4 |  | Diego De Souza | 82 | 7 |
| 5 |  | Matías Cabrera | 91 | 6 |
 | Maximiliano Gómez | 66 | 6 | |
| 7 |  | Mariano Pavone | 15 | 5 |
| 8 |  | Brahian Alemán | 48 | 4 |
 | Raúl Rivero | 23 | 4 | |
 | Diego Vera | 32 | 4 | |
| 11 |  | Adrián Balboa | 59 | 3 |
 | Gonzalo Carneiro | 41 | 3 | |
 | Facundo Milán | 41 | 3 | |
 | Rodrigo Mora | 36 | 3 | |
| 15 |  | Diego Abreu | 32 | 2 |
 | Matías Alonso | 35 | 2 | |
 | Mathías Cardacio | 156 | 2 | |
 | Pablo Hernández | 15 | 2 | |
 | Adrián Luna | 102 | 2 | |
 | Germán Rivero | 35 | 2 | |
| 21 |  | Sebastián Abreu | 6 | 1 |
 | Diego Coelho | 31 | 1 | |
 | Ignacio Colombini | 13 | 1 | |
 | Anderson Duarte | 76 | 1 | |
 | Andrés Ferrari | 30 | 1 | |
 | Pablo Forlán | 11 | 1 | |
 | Nicolás González | 34 | 1 | |
 | Aníbal Hernández | 39 | 1 | |
 | Martín Ligüera | 6 | 1 | |
 | Brian Lozano | 65 | 1 | |
 | Williams Martínez | 45 | 1 | |
 | Carlos Morales | 17 | 1 | |
 | Lautaro Navarro | 32 | 1 | |
 | José Neris | 11 | 1 | |
 | Kevin Ramírez | 13 | 1 | |
 | Felipe Rodríguez | 38 | 1 | |
 | José Luis Russo | 12 | 1 | |
 | Claudio Spinelli | 18 | 1 | |
 | Mathías Suárez | 115 | 1 | |
 | Nicolás Wunsch | 84 | 1 |