All-time best penalty takers
| # | Name | Matches | 11m | |
|---|---|---|---|---|
| 1 |  | Hugo Bargas | 112 | 8 |
 | Rafinha | 162 | 8 | |
| 3 |  | Moisés Villarroel | 118 | 7 |
| 4 |  | Sergio Almirón | 57 | 6 |
| 5 |  | Gastón Rodríguez | 39 | 5 |
| 6 |  | Alexis Blanco | 27 | 4 |
 | João Paulo | 23 | 4 | |
 | César Menacho | 186 | 4 | |
| 9 |  | Martín Alaníz | 34 | 3 |
 | Cristian Arano | 147 | 3 | |
 | Juan Carlos Arce | 69 | 3 | |
 | Koke | 28 | 3 | |
 | Pablo Salinas | 131 | 3 | |
| 14 |  | Gustavo Britos | 32 | 2 |
 | Alejandro Gómez | 170 | 2 | |
 | Julio Herrera | 97 | 2 | |
 | Mario | 16 | 2 | |
 | César Pereyra | 67 | 2 | |
 | Rafael Barros | 29 | 2 | |
 | Carlos Saucedo | 28 | 2 | |
| 21 |  | Víctor Antelo | 9 | 1 |
 | Guilmar Centella | 102 | 1 | |
 | José Chávez | 179 | 1 | |
 | Samuel Garzón | 119 | 1 | |
 | Roberto Hinojosa | 35 | 1 | |
 | Jefferson da Silva | 38 | 1 | |
 | Miguel Loaiza | 60 | 1 | |
 | Matías Manzano | 32 | 1 | |
 | Daniel Néculman | 15 | 1 | |
 | Gabriel Ríos | 41 | 1 | |
 | Juan Sánchez | 22 | 1 | |
 | Joselito Vaca | 314 | 1 | |
 | Guido Vadalá | 46 | 1 |