Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 |  | Matías Fernandez | MF | |||
| 09/2021 |  | Daniel Rojano | MF |  | Deportivo Pasto | AD Pasto |
| 09/2021 | | Diego González | FW | |||
| 09/2021 | | Bruno Piano | MA | |||
| 08/2021 | | Sergio Montero | DF |  | Cerro Largo | Cerro Largo |
| 08/2021 |  | Moises | FW |  | Fluminense de Feira - BA | Fluminense BA |
| 07/2021 | | Mauricio Fratta | GK |  | Boston River | Boston River |
| 04/2021 | | Franco Macchi | MF |  | Danubio | Danubio |
| 04/2021 |  | César Pereyra | FW |  | Deportivo Maldonado | Maldonado |
| 04/2021 | | Santiago de Ávila | DF | |||
| 04/2021 | | Fabricio Santos | MF | |||
| 04/2021 | | Borys Barone | FW | | Cerro Largo | Cerro Largo |
| 03/2021 | | Federico Antúnez | DF | |||
| 03/2021 | | Marcos Donato | GK |  | Basáñez | Basáñez |
| 03/2021 | | Luis Lima | FW | |||
| 03/2021 | | Ramiro Martínez | MA | |||
| 02/2021 | | Jonathan Soto | FW | |||
| 01/2021 | | Fernando Sellanes | MF |  | Atenas | Atenas |
| 01/2021 | | Máximo Cabral | MF | |||
| 01/2021 | | Facundo Nóbrega | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2021 | | Federico Pintos | MF |  | CA Cerro | CA Cerro |
| 01/2021 | | Uri Amaral | FW |  | Juventud de Las Piedras | Juventud |