| Date | Round | Round | H/A | Res. | |||
|---|---|---|---|---|---|---|---|
| 17.02.2008 | Matchday 1 | Matchday 1 | H | ![]() | Misiones | W | 1:0 |
| 23.02.2008 | Matchday 2 | Matchday 2 | A | ![]() | Juventud | L | 1:3 |
| 02.03.2008 | Matchday 3 | Matchday 3 | H | ![]() | Español | W | 3:1 |
| 09.03.2008 | Matchday 4 | Matchday 4 | A | ![]() | Fénix | W | 2:1 |
| 16.03.2008 | Matchday 5 | Matchday 5 | H | ![]() | Defensor | L | 0:2 |
| 23.03.2008 | Matchday 6 | Matchday 6 | A | ![]() | Bella Vista | W | 3:1 |
| 29.03.2008 | Matchday 7 | Matchday 7 | H | ![]() | River Plate | L | 0:3 |
| 06.04.2008 | Matchday 8 | Matchday 8 | H | ![]() | Liverpool FC | L | 1:4 |
| 12.04.2008 | Matchday 9 | Matchday 9 | A | ![]() | CA Cerro | L | 0:1 |
| 20.04.2008 | Matchday 10 | Matchday 10 | A | ![]() | Wanderers | L | 1:2 |
| 27.04.2008 | Matchday 11 | Matchday 11 | A | ![]() | Tacuarembó | W | 3:1 |
| 03.05.2008 | Matchday 12 | Matchday 12 | H | ![]() | Peñarol | L | 0:3 |
| 11.05.2008 | Matchday 13 | Matchday 13 | A | ![]() | Rampla Juniors | L | 3:4 |
| 17.05.2008 | Matchday 14 | Matchday 14 | A | ![]() | Nacional | W | 3:1 |
| 31.05.2008 | Matchday 15 | Matchday 15 | H | ![]() | Danubio | L | 2:3 |
Progreso















