| Date | Round | Round | H/A | Res. | |||
|---|---|---|---|---|---|---|---|
| 23.02.2008 | Matchday 2 | Matchday 2 | H | ![]() | CA Cerro | L | 0:1 |
| 27.02.2008 | Matchday 1 | Matchday 1 | A | ![]() | Nacional | L | 1:3 |
| 02.03.2008 | Matchday 3 | Matchday 3 | A | ![]() | Danubio | D | 2:2 |
| 09.03.2008 | Matchday 4 | Matchday 4 | H | ![]() | Progreso | L | 1:2 |
| 16.03.2008 | Matchday 5 | Matchday 5 | A | ![]() | Tacuarembó | D | 1:1 |
| 23.03.2008 | Matchday 6 | Matchday 6 | H | ![]() | Rampla Juniors | W | 2:0 |
| 30.03.2008 | Matchday 7 | Matchday 7 | A | ![]() | Peñarol | L | 1:2 |
| 06.04.2008 | Matchday 8 | Matchday 8 | H | ![]() | Defensor | L | 1:3 |
| 13.04.2008 | Matchday 9 | Matchday 9 | A | ![]() | Juventud | D | 1:1 |
| 19.04.2008 | Matchday 10 | Matchday 10 | H | ![]() | Liverpool FC | L | 2:3 |
| 27.04.2008 | Matchday 11 | Matchday 11 | A | ![]() | Español | L | 1:2 |
| 04.05.2008 | Matchday 12 | Matchday 12 | H | ![]() | Misiones | W | 2:0 |
| 10.05.2008 | Matchday 13 | Matchday 13 | H | ![]() | River Plate | L | 1:2 |
| 17.05.2008 | Matchday 14 | Matchday 14 | A | ![]() | Bella Vista | W | 1:0 |
| 31.05.2008 | Matchday 15 | Matchday 15 | H | ![]() | Wanderers | L | 2:3 |
Fénix















