Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2022 |  | Danielo Nuñez | MA | |||
| 07/2022 | | Edgardo Adinolfi | MA | |||
| 05/2022 | | Matías Cabrera | MF | |||
| 02/2022 | | Tabaré Viudez | MF | |||
| 02/2022 | | Anthony Hernandez | GK | |||
| 01/2022 | | Nicolás González | FW |  | River Plate | River Plate |
| 01/2022 | | Facundo Conde | GK | |||
| 01/2022 | | Brian Mancini | GK |  | Villa Teresa | Villa Teresa |
| 01/2022 | | David Silva | GK | |||
| 01/2022 | | Mathías Abero | DF |  | Montevideo Wanderers | Wanderers |
| 01/2022 | | Simon Bentancur | DF | |||
| 01/2022 | | Alan García | DF |  | Villa Española | Española |
| 01/2022 | | Andrés Lamas | DF |  | Defensor Sporting | Defensor |
| 01/2022 | | Nicolás Ramos | DF |  | Fénix | Fénix |
| 01/2022 | | Fernando Souza | DF | | Fénix | Fénix |
| 01/2022 | | Agustín Barán | MF |  | Sud América | Sud América |
| 01/2022 | | Mauricio Nuñez | MF | |||
| 01/2022 | | Hamilton Pereira | MF |  | Cerro Largo | Cerro Largo |
| 01/2022 | | Danilo Cóccaro | FW | | Villa Teresa | Villa Teresa |
| 01/2022 | | Maureen Franco | FW | | Fénix | Fénix |
| 01/2022 | | Emiliano Melo | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2022 | | Anthony Sosa | MF |  | Cerrito | Cerrito |
| 06/2022 | | Mauro Pedemonte | MF | | Villa Teresa | Villa Teresa |
| 03/2022 |  | Felipe Klein | MF |  | Glória - RS | Glória |
| 02/2022 | | Bruno Foliados | MF | | Sud América | Sud América |
| 01/2022 | | Emiliano Álvarez | DF |  | Asteras Vlachioti | Asteras Vlachioti |
| 01/2022 | | Gabriel Araújo | GK | | Villa Española | Española |
| 01/2022 | | Agustín Chopitea | DF | | River Plate | River Plate |
| 01/2022 | | Facundo Falcón | DF |  | Colón | Colón |
| 01/2022 | | Kevin Moreira | DF | | Colón | Colón |
| 01/2022 | | Christian Núñez | DF | | Sud América | Sud América |
| 01/2022 | | Nicolás Raguso | DF |  | Rocha | Rocha |
| 01/2022 | | Matías Alfonso | MF | | River Plate | River Plate |
| 01/2022 |  | Fernando Elizari | MF | | Defensor Sporting | Defensor |
| 01/2022 | | Pablo Porcile | MF |  | La Luz | La Luz |
| 01/2022 | | Diego Coelho | FW |  | Curicó Unido | Curicó Unido |
| 01/2022 | | Brian Cordara | FW | | Cerro Largo | Cerro Largo |
| 01/2022 | | Gonzalo Pintos | FW | | Colón | Colón |
| 01/2022 |  | Ignacio Yepez | FW |  | Miramar Misiones | Misiones |