Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2022 |  | Irayda Angulo | DF | |||
| 01/2022 | | Milena Bayas | DF |  | UPS Carneras | UPS |
| 01/2022 |  | Kathleen Rosales | DF |  | Técnico Universitario | Técnico Universitario |
| 01/2022 | | Viviana Bonilla | MF | |||
| 01/2022 | | Ana Carrillo | MF | |||
| 01/2022 | | Angie Freire | MF | |||
| 01/2022 | | Mayerli Montoya | MF |  | San Miguel | San Miguel |
| 01/2022 | | Britany Perdomo | MF | | Técnico Universitario | Técnico Universitario |
| 01/2022 | | Ambar Reinoso | MF | | Técnico Universitario | Técnico Universitario |
| 01/2022 | | Yuriana Avila | FW |  | Dragonas IDV | Dragonas |
| 01/2022 | | Lady Luiz | FW |  | Guayaquil City | Guayaquil City |
| 01/2022 | | Melanie Miño | FW | |||
| 01/2022 | | Katherine Olivero | FW |  | Sport JC | Sport JC |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2022 | | María Pineda | DF |  | Quito FC | Quito FC |
| 01/2022 | | Karen Chumpi | MF |  | El Nacional | El Nacional |
| 01/2022 | | Fernanda Zambrano | MF |  | Leones del Norte | Leones del Norte |
| 01/2022 | | María Mina | FW | | El Nacional | El Nacional |