Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 |  | Ariel Mina | DF |  | LDU Quito U20 | U20 |
| 09/2021 | | Denil Castillo | MF |  | LDU Quito U19 | U19 |
| 09/2021 | | Óscar Zambrano | MF | |||
| 09/2021 | | Jairón Charcopa | FW | |||
| 09/2021 | | Yeltzin Erique | DF | | LDU Quito U20 | U20 |
| 08/2021 | | Maiky De La Cruz | DF | | LDU Quito U20 | U20 |
| 08/2021 |  | Santiago Scotto | MF |  | Montevideo City Torque | Torque |
| 07/2021 | | Lenín Ayoví | GK | | LDU Quito U19 | U19 |
| 07/2021 | | José Cárdenas | GK |  | América de Quito | América |
| 07/2021 | | Daykol Romero | DF |  | Chacaritas FC | Chacaritas FC |
| 07/2021 | | Kevin Mercado | MF |  | Club Necaxa | Necaxa |
| 07/2021 | | Mathias Solis | MF | |||
| 07/2021 |  | Pablo Marini | MA | | Montevideo City Torque | Torque |
| 06/2021 | | Sebastián González | MF | |||
| 06/2021 | | Nilson Angulo | FW | |||
| 03/2021 | | Randy Meneses | MF | | LDU Quito U19 | U19 |
| 02/2021 | | Juan Kaprof | MF |  | Calcio Lecco 1912 | Calcio Lecco 19 |
| 01/2021 |  | Luis Amarilla | FW |  | Vélez Sarsfield | Vélez Sársfield |
| 01/2021 | | Gender Villarreal | GK | |||
| 01/2021 | | Carlos Rodríguez | DF |  | Delfín SC | Delfín SC |
| 01/2021 | | Byron Chala | MF | |||
| 01/2021 | | Luis Chicaiza | MF |  | Universidad Católica | Uni. Católica |
| 01/2021 | | Djorkaeff Reasco | FW |  | Dorados de Sinaloa | Dorados |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 | | Matías Zunino | MF |  | Nacional | Nacional |
| 07/2021 |  | Cristian Martínez | FW |  | Atlético Junior | Atlético Junior |
| 07/2021 | | Leonel Nazareno | GK | | Chacaritas FC | Chacaritas FC |
| 04/2021 | | Carlos Rodríguez | DF |  | Peñarol | Peñarol |
| 01/2021 | | Luis Chicaiza | MF |  | Deportivo Cuenca | Cuenca |
| 01/2021 | | Jeremy Batioja | MF |  | Aucas | SD Aucas |
| 01/2021 | | Júnior Sornoza | MF |  | Club Tijuana | Club Tijuana |
| 01/2021 | | Edison Vega | MF | | Aucas | SD Aucas |
| 01/2021 | | Davinson Jama | FW | | Universidad Católica | Uni. Católica |
| 01/2021 | | Ronny Medina | FW | | América de Quito | América |