Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 |  | Ivo Basay | MA | |||
| 09/2021 | | Leonardo Valencia | MF |  | Colo-Colo | Colo-Colo |
| 09/2021 | | Óscar Correa | MA | |||
| 08/2021 | | Lucas Alarcón | DF |  | Universidad de Chile | Uni. de Chile |
| 08/2021 |  | Juan Cavallaro | MF |  | Tigre | C. A. T. |
| 08/2021 | | Matías Cortés | DF | |||
| 08/2021 |  | Victor Ramon | DF | |||
| 07/2021 | | Valentin Coria | FW | |||
| 06/2021 | | Luckas Carreño | MF | |||
| 04/2021 |  | Jorge Benítez | FW |  | Sol de América | Sol de América |
| 03/2021 | | Leandro Díaz | DF |  | Universidad de Concepción | Universidad de Concepción |
| 03/2021 | | Jimmy Martínez | MF | | Universidad de Chile | Uni. de Chile |
| 03/2021 | | Jaime Carreño | MF | |||
| 03/2021 | | Mauricio Asenjo | FW |  | Banfield | Banfield |
| 03/2021 |  | Felipe Jaramillo | MF |  | América de Cali | América |
| 03/2021 | | Ángelo Quiñones | MF | |||
| 03/2021 | | Matías Fernández | MF | | Colo-Colo | Colo-Colo |
| 03/2021 |  | César Munder | FW | |||
| 03/2021 | | Guillermo Zuleta | MF | |||
| 02/2021 | | Maximiliano Guerrero | MF |  | Rangers | Rangers |
| 01/2021 | | Mauro Pizarro | GK |  | La Serena U20 | U20 |
| 01/2021 | | Francisco Diaz | MF | |||
| 01/2021 | | Santiago Dittborn | MF | |||
| 01/2021 | | Martin Ramirez | MF | |||
| 01/2021 | | Mauricio Regodeceves | MF |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 | | Humberto Suazo | FW |  | CF Monterrey II | CF Monterrey II |
| 08/2021 |  | Danny Pérez | FW |  | Deportivo Lara | CD Lara |
| 07/2021 | | Mauricio Asenjo | FW |  | Independiente Rivadavia | CSIR |
| 07/2021 | | David Montoya | DF |  | Leones FC | Leones FC |
| 07/2021 | | Rodrigo Salinas | FW |  | Sarmiento de Junín | Sarmiento |
| 03/2021 | | Stéfano Magnasco | DF |  | Unión Española | Unión Española |
| 03/2021 | | Sergio Arriagada | MF |  | Barnechea | Barnechea |
| 03/2021 | | Nicolás Baeza | MF |  | Huachipato | Huachipato |
| 03/2021 | | Jaime Valdés | MF |  | San Antonio Unido | San Antonio |
| 03/2021 | | Felipe Barrientos | FW |  | Curicó Unido | Curicó Unido |
| 03/2021 | | Fabián Hormazábal | FW |  | O'Higgins | O'Higgins |
| 03/2021 | | Walter Ponce | FW | | Barnechea | Barnechea |
| 02/2021 | | Gustavo Fuentealba | GK |  | Puerto Montt | Puerto Montt |
| 02/2021 | | Gerónimo Poblete | MF |  | Vélez Sarsfield | Vélez Sársfield |
| 02/2021 | | Nicolás Nocetti | GK |  | Sarmiento de Junín II | CA Sarmiento II |