Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 07/2021 |  | Maximilian Eckert |  | TSG Hoffenheim II U15 | U15 | |
| 07/2021 | | Fabian Kuhnke | | TSG Hoffenheim II U15 | U15 | |
| 07/2021 | | Imam Toraman | | TSG Hoffenheim II U15 | U15 | |
| 07/2021 | | Luis Bicking | GK |  | 1. FSV Mainz 05 U15 | Mainz 05 U15 |
| 07/2021 | | Henri Eckelmann | GK | |||
| 07/2021 | | Kevin Malaka | GK |  | FC-Astoria Walldorf U15 | U15 |
| 07/2021 | | Mark Bouzelha | DF |  | SV Darmstadt 98 U15 | U15 |
| 07/2021 |  | Tyrone Jarrett | DF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Marc Kaiser | DF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Luca Provvido | DF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Maximilian Theuer | DF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Nevio Bove | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Romeo Di Mauro | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Arda Elmas | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Jakob Meeß | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | Nevio Ostheimer | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 |  | Enis Redzepi | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 |  | Safouan Zbiri | MF |  | TSG Hoffenheim II U17 | U17 |
| 07/2021 | | Neno Žeželj | MF | | TSG Hoffenheim II U15 | U15 |
| 07/2021 |  | Zain Biazid | FW | | TSG Hoffenheim II U15 | U15 |
| 07/2021 | | David Creța | FW |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 09/2021 | | Matej Jelavic |  | SSV Ulm 1846 U15 | U15 | |
| 07/2021 | | Finn Wyslich |  | Stuttgarter Kickers U15 | U15 | |
| 07/2021 | | Ferdinand Gebert | GK |  | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Tom Gerlach | GK |  | SV Böblingen U15 | U15 |
| 07/2021 | | Abba Camara | DF | | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Darius Germann | DF |  | 1. FC Heidenheim 1846 II U17 | U17 |
| 07/2021 | | Baton Hajrizaj | MF | | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Melvin Onos | MF | | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Leonard Krasniqi | FW | | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Luigi Mignano | FW | | TSG Hoffenheim U17 | Hoffenheim U17 |
| 07/2021 | | Amour Nnokoson | FW |  | SV Sandhausen U17 | U17 |