Additions
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 03/2022 |  | Ali Kalla | DF |  | Angers SCO B | Angers SCO II |
| 03/2022 |  | Yassin Belkhdim | MF | | Angers SCO B | Angers SCO II |
| 01/2022 |  | Marin Jakoliš | FW |  | HNK Šibenik | HNK Šibenik |
| 01/2022 | | Jason Mbock | FW | | Angers SCO B | Angers SCO II |
| 01/2022 | | Guédé Nadje | FW | | Angers SCO B | Angers SCO II |
| 01/2022 | | Mattéo Corduan | MF | | Angers SCO B | Angers SCO II |
| 01/2022 | | Daylam Meddah | MF | | Angers SCO B | Angers SCO II |
| 01/2022 |  | Nabil Bentaleb | MF | |||
| 12/2021 |  | Frank Magri | FW | | Angers SCO B | Angers SCO II |
| 09/2021 | | Bilal Brahimi | FW |  | Stade de Reims | Stade Reims |
| 07/2021 | | Batista Mendy | MF |  | FC Nantes | FC Nantes |
| 07/2021 | | Anthony Mandrea | GK |  | SO Cholet | SO Cholet |
| 07/2021 | | Azzedine Ounahi | MF |  | US Avranches | US Avranches |
| 07/2021 |  | Casimir Ninga | FW |  | Sivasspor | Sivasspor |
| 07/2021 | | Olivier Tingry | GK-CO | |||
| 07/2021 | | Jean-Jacques Batoum | AT-C | | Angers SCO B | Angers SCO II |
| 07/2021 | | Alan Berrou | AT-C |  | Angers SCO U19 | U19 |
| 07/2021 | | Julien Le Goux | G-AN |  | Olympique Lyonnais | Lyonnais |
Departures
| from | Name | Pos | Team | Team | ||
|---|---|---|---|---|---|---|
| 01/2022 | | Bilal Brahimi | FW |  | OGC Nice | Nice |
| 01/2022 | | Antonin Bobichon | MF |  | AS Nancy Lorraine | AS Nancy |
| 01/2022 | | Farid El Melali | FW |  | Pau FC | Pau FC |
| 01/2022 | | Frank Magri | FW |  | SC Bastia | Bastia |
| 01/2022 | | Paul Bernardoni | GK |  | AS Saint-Étienne | Saint-Étienne |
| 01/2022 |  | Sada Thioub | FW | | AS Saint-Étienne | Saint-Étienne |
| 08/2021 | | Mateo Pavlović | DF |  | Amiens SC | Amiens |
| 08/2021 | | Rachid Alioui | FW |  | KV Kortrijk | Kortrijk |
| 08/2021 |  | Thomas Touré | FW |  | Excelsior Virton | Virton |
| 08/2021 |  | Yassin Fortuné | FW | | SO Cholet | SO Cholet |
| 07/2021 |  | Lassana Coulibaly | MF |  | US Salernitana 1919 | Salernitana |
| 07/2021 | | Ludovic Butelle | GK |  | Red Star FC | Red Star |
| 07/2021 | | Loïs Diony | FW |  | Crvena Zvezda | Crv. Zvezda |
| 07/2021 | | Oussama Falouh | DF | | US Avranches | US Avranches |
| 07/2021 |  | Kévin Mouanga | DF |  | FC Annecy | FC Annecy |
| 07/2021 | | Ibrahim Amadou | MF |  | Sevilla FC | Sevilla |