Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 18.07.2021 |  | Matchday 1 | Khimik Dzerzhinsk - Enisey Krasnoyarsk 2 | - | 0:1 | |
| 24.07.2021 | | Matchday 2 | Khimik Dzerzhinsk - FK Chertanovo | - CHE | 0:0 | |
| 07.08.2021 | | Matchday 4 | Khimik Dzerzhinsk - Olimp-Dolgoprudny 2 | - | 2:0 | |
| 21.08.2021 | | Matchday 6 | Khimik Dzerzhinsk - Kazanka | - | 1:2 | |
| 04.09.2021 | | Matchday 8 | Khimik Dzerzhinsk - FK Murom | - | 2:1 | |
| 14.09.2021 | | Matchday 10 | Khimik Dzerzhinsk - Znamya Truda | - | 2:1 | |
| 10.10.2021 | | Matchday 15 | Khimik Dzerzhinsk - Torpedo Vladimir | - | 0:0 | |
| 19.10.2021 | | Matchday 17 | Khimik Dzerzhinsk - Din. Moskva 2 | - | 0:1 | |
| 31.10.2021 | | Matchday 19 | Khimik Dzerzhinsk - FK Volna | - | 0:1 | |
| 10.11.2021 | | Matchday 21 | Khimik Dzerzhinsk - Shinnik | - Shi | 2:2 | |
| 26.11.2021 |  | Matchday 17 | FK Nizhny Novgorod - Krylia Sovetov | - | 0:2 | Unter Ausschluss der Öffentlichkeit. |
| 03.12.2021 | | Matchday 18 | FK Nizhny Novgorod - Akademiya Konopleva | - | 5:2 | 50 |