Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 31.01.2021 |  | Matchday 8 | Fiorentina - Inter | - INT | 2:1 | |
| 17.02.2021 | | Matchday 10 | Fiorentina - Atalanta | - | 3:3 | |
| 06.03.2021 | | Matchday 13 | Fiorentina - AC Milan | - | 3:1 | |
| 14.03.2021 | | Matchday 15 | Fiorentina - Sassuolo | - | 1:1 | |
| 03.04.2021 | | Matchday 17 | Fiorentina - Ascoli | - | 5:2 | |
| 24.04.2021 | | Matchday 20 | Fiorentina - Empoli FC | - | 0:4 | |
| 09.05.2021 | | Matchday 22 | Fiorentina - Genoa CFC | - | 0:2 | |
| 21.05.2021 | | Matchday 24 | Fiorentina - SPAL 2013 Ferrara | - | 1:2 | |
| 30.05.2021 | | Matchday 26 | Fiorentina - Torino FC | - TOR | 2:2 | |
| 04.06.2021 | | Matchday 27 | Fiorentina - Juventus | - JUV | 0:1 | |
| 12.06.2021 | | Matchday 29 | Fiorentina - Sampdoria | - | 1:1 | |
| 28.08.2021 | | Matchday 1 | Fiorentina - Juventus | - JUV | 1:2 | |
| 23.10.2021 | | Matchday 6 | Fiorentina - Pescara | - | 2:1 | |
| 06.11.2021 | | Matchday 8 | Fiorentina - Atalanta | - | 1:0 | |
| 28.11.2021 | | Matchday 10 | Fiorentina - Genoa CFC | - | 0:0 | |
| 01.12.2021 |  | Round of 16 | Fiorentina - AC Milan | - | 4:3 | |
| 13.12.2021 | | Matchday 12 | Fiorentina - Torino FC | - TOR | 2:3 |