Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 25.02.2004 |  | Group 5 | Nacional - Independiente | Nac - IND | 0:0 | |
| 02.03.2004 | | Group 1 | Peñarol - São Caetano | PEN - São | 1:1 | |
| 04.03.2004 | | Group 5 | Nacional - Cienciano | Nac - CSC | 1:0 | |
| 16.03.2004 | | Group 1 | Peñarol - The Strongest | PEN - STR | 4:0 | |
| 01.04.2004 |  | Matchday 5 | Uruguay - Venezuela | URU - VEN | 0:3 | 48.000 |
| 16.04.2004 | | Group 1 | Peñarol - CF América | PEN - CFA | 2:0 | |
| 21.04.2004 | | Group 5 | Nacional - El Nacional | Nac - ELN | 3:2 | |
| 13.05.2004 | | Round of 16 2nd leg | Nacional - Táchira | Nac - Tác | 2:2 | |
| 02.06.2004 | | Matchday 6 | Uruguay - Peru | URU - PER | 1:3 | 30.000 |
| 05.09.2004 | | Matchday 8 | Uruguay - Ecuador | URU - ECU | 1:0 | 28.000 |
| 09.09.2004 |  | 2. Round First leg | Danubio - Peñarol | Dan - PEN | 1:2 | |
| 21.09.2004 | | 2. Round 2nd leg | Peñarol - Danubio | PEN - Dan | 1:1 | |
| 06.10.2004 | | Round of 16 First leg | Peñarol - Cerro Porteño | PEN - Cer | 1:3 | |
| 17.11.2004 | | Matchday 11 | Uruguay - Paraguay | URU - PAR | 1:0 | 35.000 |