Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 09.04.1980 |  | Group 2 | Nacional - Defensor | Nac - Def | 1:0 | 25.000 |
| 17.04.1980 | | Group 2 | The Strongest - Nacional | STR - Nac | 3:0 | 15.000 |
| 23.04.1980 | | Group 2 | Defensor - Nacional | Def - Nac | 0:3 | 23.610 |
| 27.04.1980 | | Group 2 | Nacional - Petrolero | Nac - ORI | 5:0 | 9.000 |
| 27.04.1980 | | Group 2 | Defensor - The Strongest | Def - STR | 1:1 | 9.000 |
| 30.04.1980 | | Group 2 | Nacional - The Strongest | Nac - STR | 2:0 | 40.000 |
| 30.04.1980 | | Group 2 | Defensor - Petrolero | Def - ORI | 1:1 | 40.000 |
| 02.07.1980 | | Group B | Nacional - Olimpia | Nac - Oli | 1:1 | 34.401 |
| 16.07.1980 | | Group B | Nacional - O'Higgins | Nac - HIG | 2:0 | 36.160 |
| 06.08.1980 | | Final 2nd leg | Nacional - Internacional | Nac - INT | 1:0 | 65.000 |
| 08.12.1980 |  | December | Uruguay - Finland | URU - FIN | 6:0 | 10.000 |
| 30.12.1980 | | December | Uruguay - Netherlands | URU - NED | 2:0 | 65.000 |