Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 06.02.2022 |  | Matchday 3 | Barranquilla FC - Real Cartagena | - Rea | 0:2 | |
| 19.02.2022 | | Matchday 5 | Barranquilla FC - Atlético FC | - | 1:0 | |
| 06.03.2022 | | Matchday 7 | Barranquilla FC - Bogotá FC | - | 2:4 | |
| 16.04.2022 | | Matchday 13 | Barranquilla FC - Real Soacha | - | 1:1 | |
| 04.05.2022 | | Matchday 15 | Barranquilla FC - Fortaleza | - | 0:1 | |
| 17.07.2022 | | Matchday 2 | Barranquilla FC - Tigres | - | 3:0 | |
| 04.08.2022 | | Matchday 5 | Barranquilla FC - Boca Juniors | - BOC | 1:1 | |
| 09.08.2022 | | Matchday 6 | Barranquilla FC - Leones FC | - | 3:1 | |
| 04.09.2022 | | Matchday 10 | Barranquilla FC - Atlético Huila | - Atl | 2:1 | |
| 14.09.2022 | | Matchday 12 | Barranquilla FC - Real Santander | - | 2:1 | |
| 25.09.2022 | | Matchday 14 | Barranquilla FC - Real Cartagena | - Rea | 2:3 | |
| 08.10.2022 | | Matchday 16 | Barranquilla FC - Orsomarso SC | - | 2:0 | |
| 19.10.2022 | | Group A | Barranquilla FC - Fortaleza | - | 0:1 | |
| 21.10.2022 | | Group A | Barranquilla FC - Llaneros FC | - LLA | 2:2 | |
| 07.11.2022 | | Group A | Barranquilla FC - Boyacá Chicó | - Boy | 0:2 |