Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 24.01.2016 |  | Matchday 1 | Nacional - Club Guaraní | Nac - Gua | 2:1 | 703 |
| 14.02.2016 | | Matchday 5 | Nacional - Libertad | Nac - LIB | 1:3 | 522 |
| 20.02.2016 | | Matchday 6 | Nacional - Ríver Plate | Nac - CRP | 0:0 | 374 |
| 27.02.2016 | | Matchday 7 | Ríver Plate - Club Guaraní | CRP - Gua | 1:1 | 544 |
| 03.03.2016 | | Matchday 8 | Nacional - General Díaz | Nac - CGD | 1:3 | 296 |
| 07.04.2016 | | Matchday 13 | Nacional - Club Rubio Ñu | Nac - Rub | 3:1 | 340 |
| 30.04.2016 | | Matchday 18 | Nacional - Capiatá | Nac - CDC | 0:1 | 238 |
| 22.05.2016 | | Matchday 22 | Nacional - Caballero | Nac - GC | 2:3 | 279 |
| 09.07.2016 | | Matchday 1 | Nacional - Capiatá | Nac - CDC | 2:2 | 334 |
| 21.07.2016 | | Matchday 3 | Nacional - Sol de América | Nac - Sol | 2:1 | 331 |
| 26.07.2016 | | Matchday 4 | Nacional - Luqueño | Nac - CSL | 1:2 | 357 |
| 10.09.2016 | | Matchday 10 | Nacional - Caballero | Nac - GC | 4:1 | 324 |
| 30.10.2016 | | Matchday 16 | Nacional - Libertad | Nac - LIB | 1:2 | 345 |
| 21.11.2016 | | Matchday 18 | Nacional - Club Guaraní | Nac - Gua | 1:1 | 654 |
| 04.12.2016 | | Matchday 20 | Nacional - Club Rubio Ñu | Nac - Rub | 3:1 | 305 |
| 18.12.2016 | | Matchday 22 | Nacional - Ríver Plate | Nac - CRP | 2:0 | 273 |