Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 07.08.2021 |  | 1. Round | Greifswald - Augsburg | GFC - FCA | 2:4 | 4.000 |
| 14.08.2021 |  | Matchday 2 | Greifswald - Rostocker FC | GFC - RFC | 2:1 | 540 |
| 22.08.2021 | | Matchday 4 | Greifswald - Lok Stendal | GFC - STE | 2:0 | 383 |
| 10.09.2021 | | Matchday 6 | Greifswald - MSV Pampow | GFC - | 1:2 | 406 |
| 15.09.2021 | | Matchday 3 | Greifswald - Rostock II | GFC - Ros | 1:1 | 321 |
| 26.09.2021 | | Matchday 8 | Greifswald - Stern 1900 | GFC - | 4:2 | 272 |
| 17.10.2021 | | Matchday 10 | Greifswald - RSV Eintracht | GFC - RSV | 2:2 | 252 |
| 31.10.2021 | | Matchday 12 | Greifswald - Vict. Seelow | GFC - | 2:1 | 304 |
| 20.11.2021 | | Matchday 14 | Greifswald - SC Staaken | GFC - SC | 0:2 | 280 |