Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 26.03.2021 |  | Matchday 1 | Galway - Shelbourne FC | - SHE | 0:0 | |
| 16.04.2021 | | Matchday 4 | Galway - Treaty United | - | 1:1 | |
| 23.04.2021 | | Matchday 5 | Galway - UC Dublin | - UC | 2:2 | |
| 07.05.2021 | | Matchday 7 | Galway - Bray Wanderers | - Bra | 1:2 | |
| 14.05.2021 | | Matchday 8 | Galway - Wexford FC | - | 1:0 | |
| 11.06.2021 | | Matchday 11 | Galway - Athlone Town | - Ath | 2:1 | 100 |
| 18.06.2021 | | Matchday 12 | Galway - Cabinteely FC | - | 1:0 | 100 |
| 09.07.2021 | | Matchday 15 | Galway - Cobh Ramblers | - Cob | 2:0 | |
| 06.08.2021 | | Matchday 18 | UC Dublin - Shelbourne FC | UC - SHE | 0:0 | |
| 13.08.2021 | | Matchday 19 | Galway - Shelbourne FC | - SHE | 3:1 | |
| 10.09.2021 | | Matchday 22 | Galway - Treaty United | - | 0:0 | |
| 24.09.2021 | | Matchday 23 | Galway - UC Dublin | - UC | 4:1 | |
| 15.10.2021 | | Matchday 26 | Cobh Ramblers - Shelbourne FC | Cob - SHE | 2:0 | |
| 22.10.2021 | | Matchday 25 | Galway - Bray Wanderers | - Bra | 1:0 | |
| 07.11.2021 |  | 1. Round 2nd leg | Galway - Bray Wanderers | - Bra | 0:1 |