Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 04.04.2010 |  | Matchday 2 | DC United - New Engl. | DCU - NER | 0:2 | 20.664 |
| 18.04.2010 | | Matchday 2 | DC United - Chicago Fire | DCU - CHI | 0:2 | 18.407 |
| 01.05.2010 | | Matchday 3 | DC United - New York RB | DCU - RB | 0:2 | 12.089 |
| 06.05.2010 | | Matchday 3 | DC United - Kansas City | DCU - SKC | 2:1 | 10.038 |
| 16.05.2010 | | Matchday 3 | DC United - Colorado Rapids | DCU - COR | 0:1 | 13.570 |
| 30.05.2010 | | Matchday 3 | DC United - Chivas USA | DCU - Chi | 3:2 | 13.043 |
| 06.06.2010 | | Matchday 4 | DC United - Salt Lake | DCU - RSL | 0:0 | 15.328 |
| 16.07.2010 | | Matchday 5 | DC United - Seattle SFC | DCU - SEA | 0:1 | 13.716 |
| 19.07.2010 | | Matchday 5 | DC United - L.A. Galaxy | DCU - LAG | 1:2 | 17.688 |
| 15.08.2010 | | Matchday 6 | DC United - FC Dallas | DCU - DAL | 1:3 | 12.474 |
| 22.08.2010 | | Matchday 6 | DC United - Philadelphia | DCU - PHI | 2:0 | 12.165 |
| 05.09.2010 | | Matchday 7 | DC United - Columbus Crew | DCU - COC | 0:1 | 12.075 |
| 08.09.2010 |  | September | El Salvador - Guatemala | SLV - GUA | 0:2 | |
| 26.09.2010 | | Matchday 7 | DC United - H. Dynamo | DCU - HOU | 1:3 | 13.828 |
| 10.10.2010 | | Matchday 8 | DC United - Earthquakes | DCU - SJE | 0:2 | 14.822 |
| 24.10.2010 | | Matchday 8 | DC United - Toronto FC | DCU - TOR | 2:3 | 18.071 |