Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 28.08.2021 |  | Matchday 2 | Sporting Charleroi - RSC Anderlecht | - | 1:4 | |
| 11.09.2021 | | Matchday 4 | Sporting Charleroi - Sint-Truidense VV | - | 1:1 | |
| 25.09.2021 | | Matchday 6 | Sporting Charleroi - KV Mechelen | - | 2:1 | |
| 02.10.2021 | | Matchday 7 | Sporting Charleroi - SV Zulte Waregem | - | 2:1 | |
| 30.10.2021 | | Matchday 11 | Sporting Charleroi - KRC Genk | - | 1:4 | |
| 20.11.2021 | | Matchday 13 | Sporting Charleroi - Royal Antwerp FC | - | 1:0 | |
| 27.11.2021 | | Matchday 14 | Sporting Charleroi - KVC Westerlo | - | 2:0 |