Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 08.08.2021 |  | Matchday 5 | Metallurg Lipetsk - Rotor Volgograd | - | 0:1 | 2.200 |
| 21.08.2021 | | Matchday 7 | Metallurg Lipetsk - FK Krasnodar 2 | - | 1:2 | Unter Ausschluss der Öffentlichkeit. |
| 05.09.2021 | | Matchday 9 | Metallurg Lipetsk - Enisey | - Eni | 0:2 | 650 |
| 15.09.2021 | | Matchday 11 | Metallurg Lipetsk - Spartak 2 | - | 0:2 | 700 |
| 25.09.2021 | | Matchday 13 | Metallurg Lipetsk - Teks. Ivanovo | - | 0:0 | 500 |
| 03.10.2021 | | Matchday 15 | Metallurg Lipetsk - SKA-Khabarovsk | - SKA | 1:1 | 550 |
| 13.10.2021 | | Matchday 17 | Metallurg Lipetsk - Veles | - FVM | 1:0 | 700 |
| 17.10.2021 | | Matchday 18 | Metallurg Lipetsk - Baltika | - BAL | 0:4 | 750 |
| 26.10.2021 |  | Group 10 | Metallurg Lipetsk - CSKA Moskva | - CSK | 0:2 | |
| 31.10.2021 | | Matchday 20 | Metallurg Lipetsk - FK Orenburg | - | 1:0 | 750 |
| 13.11.2021 | | Matchday 22 | Metallurg Lipetsk - FK Neftekhimik | - NEF | 1:2 | 600 |
| 21.11.2021 | | Matchday 24 | Metallurg Lipetsk - FK Kamaz | - FK | 0:1 | 1.000 |