Gameplan
| Date | Round | Match | Match | Res. | Attendance | |
|---|---|---|---|---|---|---|
| 20.02.2022 |  | Matchday 3 | Caballero - Tacuary | GCD - TFC | 2:0 | |
| 26.03.2022 | | Matchday 4 | Sol de América - Olimpia | Sol - Oli | 0:1 | |
| 25.06.2022 | | Matchday 21 | Caballero - Resistencia | GCD - RSC | 2:1 | |
| 17.07.2022 | | Matchday 1 | Caballero - Nacional | GCD - Nac | 1:2 | |
| 30.07.2022 | | Matchday 4 | Ameliano - Cerro Porteño | CSA - Cer | 0:2 | |
| 27.08.2022 | | Matchday 8 | Caballero - Cerro Porteño | GCD - Cer | 1:1 | |
| 04.09.2022 | | Matchday 9 | 12 de Octubre - Olimpia | 12 - Oli | 1:3 | |
| 02.10.2022 | | Matchday 14 | Guaireña - Olimpia | GFC - Oli | 0:1 | |
| 23.10.2022 | | Matchday 18 | Club Guaraní - Cerro Porteño | Gua - Cer | 1:2 |